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From Longevity to Precision Healthy Ageing: A Structured Evidence-Based Approach to Clinical Assessment and Intervention

Event Description

Longevity science is moving from the search for individual “anti-ageing” interventions towards understanding why people age differently and how this knowledge might extend health span. Genetics, epigenetics, nutrition and lifestyle interact with key ageing pathways involving mTOR, AMPK, sirtuins, autophagy, mitochondrial function and inflammation. Crucially, many of these pathways respond to diet and lifestyle, creating opportunities to personalise healthy-ageing strategies according to individual biology.

This idea underpins precision nutrition for healthy ageing, which aims to combine genomic, metabolomic and microbiome information with targeted dietary interventions. Biological ageing measures, including DNA methylation-based epigenetic clocks, could also help assess responses. However, making a biological-age marker appear “younger” is not necessarily the same as improving healthspan. These tools still need to demonstrate that biomarker changes translate into meaningful outcomes such as reduced disease risk, preserved function and increase health span.

The emerging picture is therefore one of precision longevity built on established prevention. Nutrition, physical activity, early detection and other preventive measures provide the foundation, with genetics, advanced biomarkers, and supplements layered on according to individual need and strength of evidence. Rather than replacing conventional prevention, precision tools may ultimately help make it more targeted, measurable and effective.

Learning Objectives

  • Review how genes, lifestyle and environment influence the biology of ageing.
  • Identify key ageing pathways influenced by nutrition and lifestyle medicine.
  • Recognise the potential and limitations of assessments including nutritional biomarkers, biological hallmarks of aging, and biological-age clocks.
  • Explore a structured, evidence-based approached to assessment and management featuring personalised nutrition and lifestyle medicine.
  • Critique the evidence for current nutritional and lifestyle approaches used in healthy-ageing strategies, including dietary supplements and dietary trends.

All attendees will receive

  • 2-hours of CPD approved education
  • Lecture notes
  • Supplementary research papers
  • Dinner and drinks
  • Free sample products

Dates and Locations

 
Cork, Radisson Blu Hotel, 11 November 2026
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Dublin, Talbot Hotel Stillorgan, 12 November 2026
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Exeter, Hotel Du Vin, 17 November 2026
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London, Millennium Gloucester, 18 November 2026
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Manchester, Malmaison, 19 November 2026
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